Hyaluronic acid gel fillers are injected to restore volume lost due to age or disease, provide facial contour, and help maintain a youthful appearance. Filler injection has become one of the most commonly performed procedures in a dermatology cosmetic practice. There exist many different types of hyaluronic acid gel fillers that differ in their hyaluronic acid concentration, particle size, cross-linking density, duration, and presence of lidocaine. High-density, large-particle fillers are recommended for deep dermal injections while the low-density, small-particle fillers are recommended for fine lines. Hyaluronic acid filler has become popular because of its low allergic response, ease of injection, rapid recovery, reproducibility, and immediate results.

Hyaluronic Acid

Common Injection Sites
Nasolabial folds
Melolabial folds
Malar hollows
Infraorbital hollows
Perioral rhytids

Calcium Hydroxyapatite

Luminera Crystalys is a sterilised apyrogenic injectable facial implant. It is a homogenous, semi-solid and completely bio-degradable implant intended for sub and deep dermal use.
It is based on calcium hydroxyapatite, the major content of teeth and bones. Crystalys is a long lasting yet non-permanent implant.
The Calcium Hydroxyapatite and gel carrier in Crystalys form a network which enhances the penetration of surrounding cells and acts as a platform in which these cells can grow. The gel carrier is then gradually absorbed leaving a long lasting implant made of new cells and calcium hydroxyapatite particles. Over time the calcium hydroxyapatite particles are degraded leaving only calcium and phosphate ions, which undergo normal homeostatic processes.

How does it Work?

Crystalys contains 55% calcium hodroxyapatite microspheres.

Crystalys is intended for deep and sub dermal tissue augmentation at the facial area. It is used for general restoration of the face and specifically for filling deep wrinkles and lines.

Crystalys works in two complementing ways:

As the dermal filler is injected, it lifts and adds volume to the injected area, thus getting immediate results.  With time, the injected filler acts as a natural scaffold for endogenous collagen, enabling collagen growth.  This process restores skin radiance, freshness and firmness and lasts for several months, therefore extending the initial effect for a long time, significantly more than hysluronic acid-based dermal fillers.

Crystalys Dermal Fillers, based on natural components, is biodegradable and non-permanent.  It is cleared from the body with no side effects, as the body recognises it as a part of its own.

The treatment is safe, long lasting and naturally based.

During the preliminary trials of the product, more than 1000 Crystalys syringes were injected with excellent safety and efficacy profile.
The product is approved by the Israeli Ministry of Health and is CE Marked.



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